IN SILICO- MOLECULAR DOCKING STUDIES OF SIDDHA POLY HERBAL FORMULATION FOR TREATMENT OF YONI SOOLAI (ENDOMETRIAL INFLAMMATION) BY SUPPRESSION OF INTERLEUKIN-6 ACTIVITY
P. Hemavathi*, Neethu P., Vignesh K., Pavithra S. and Balamurugan S.
ABSTRACT
Background: Indian medicine is the most comprehensive and rich heritage of Traditional medicine in the world.
Traditional medicine according to the definition of WHO is “The sum of Knowledge based on theories, beliefs and
experiences skill, originating from different cultures’’. WHO states that Endometriosis affects roughly 190 million
of reproductive age women and girls globally. It is a chronic disease associated with severe, life impacting pain
during menstruation, sexual intercourse, bowel movements and or urination, chronic pelvic pain, abdominal
bloating, nausea, fatigue, and some times depression, anxiety and infertility. Access to early diagnosis and
effective treatment of endometrial inflammation is important. Endometrial inflammation is one of the chronic
inflammatory diseases that mentioned in siddha Literature. Inter leukin - 6 has extensive anti – inflammatory
functions in its role as a to myokine. IL 6 was first myokine that was fond to be secreted into the blood stream in
response to muscle contractions.
Keywords: Siddha formulation, Endometrial inflammation, Inter leukin-6, inflammatory action.
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