European Journal of Biomedical and Pharmaceutical Sciences

FORMULATION AND IN-VITRO EVALUATION OF ORO-DISPERSIBLE TABLET OF ACETOAMINOPHEN MODEL DRUG BY USING SPRAY DRYING TECHNIQUE

Dr. (H.C.) Santosh D Navale*

ABSTRACT

Present study was carried out with to mask the bitter taste of Acetoaminophen by spray drying technique with help of NISSO-Nipon (L-HPC). The disintegrate the tablet as quick as possible to improve the dissolution of the drug. To develop a physically and chemically stable ODT employing suitable technique i.e., spray drying and evaluate the formulation of Acetoaminophen oral dispersible tablets hence confirmation of better formulation. The ODT Tablets characterized by FTIR, UV, solubility study, dissolution studies in different models.

Keywords: Spray Drying Technique, UV, FTIR, Dissolution Studies, Kinetic Models.