TRIPHYTOCHEMISTRY AND ANTIBACTERIAL ACTIVITY OF 70% ETHANOLIC AND AQUEOUS EXTRACTS OF THE ROOTS OF UAPACA GUINEENSIS MÜLL. ARG. (EUPHORBIACEAE)
Agre Don Josette*, Yeo Sounta Oumar, Sylla Youssouf, Silue Kalamourou, Doumbia Idrissa, Guessennd Kouadio Nathalie and Coulibaly Adama
ABSTRACT
The aim of this study was to scientifically validate the therapeutic virtues attributed to the roots of Uapaca guineensis müll. arg. (Euphorbiaceae), A plant used in the treatment of gastro-enteritis and male infertility in the department of Man (western Côte d'Ivoire). The aim was to carry out a phytochemical study and evaluate the antibacterial activity of aqueous (EAq) and ethanolic 70% (EEth70%) extracts of the plant's roots on four strains. the best performance was observed with EEth70%. Phytochemical analysis of the roots revealed the presence of most of the compounds of interest. However, alkaloids and gall tannins were absent from both extracts. In terms of antibacterial activity, inhibition diameters ranged from 06 to 20 mm for the ethanolic extract and from 06 to 15 mm for the aqueous extract. The ethanolic extract gave better inhibitory activity on the growth of the strains tested, especially on Staphylococcus aureus and Escherichia coli, with the highest inhibition diameters. Both extracts were less active on Pseudomonas aeruginosa and Klebsiella pneumoniae. In view of the results obtained, the plant could be used against various infectious pathologies.
Keywords: Uapaca guineensis, Antibacterial, Triphytochemistry, Côte d’Ivoire.
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