European Journal of Biomedical and Pharmaceutical Sciences

CAVUM METASTATIC CANCER EXPERIENCE OF THE MEDICAL ONCOLOGY DEPARTMENT OF THE MOULAY ISMAIL MILITARY HOSPITAL IN MEKNES (BASED ON 15 CASES)

M. Toreis*, A. Z. Bazine, Y. Touimri and M. Fetohi

ABSTRACT

Cavum cancers represent a specific entity different from the rest of head and neck cancers. In Morocco, cavum cancer is the second most common cancer of the head and neck after laryngeal cancer. We conducted a retrospective study of 15 cases of metastatic cavum cancer collected in the medical oncology department of the Moulay Ismail military hospital in Meknes over a five-year period from January 1, 2014 to December 31, 2019. The patients were 10 men (70%) and 5 women (30%) with an average age of 50 years with extremes of 27 and 66 years. Diagnosis is often late with a revealing symptomatology dominated by cervical adenopathy (87%). The most dominant histological type was UCNT in all cases. 80% of our patients had secondary bone localizations, associated in 26.66% of cases with extra-bone metastases (lung, liver, lymph nodes...). The treatment was based on palliative chemotherapy, with platinum salt as first-line treatment, administered in 86.7% of our patients. Second-line chemotherapy was introduced in 46.7% of patients. Cavum radiotherapy was performed in 66.7% of patients, of which 7 patients were metastatic at the outset. The average overall survival of our patients was: 20 months and 1 week with extremes between 6 months and 36 months.

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