European Journal of Biomedical and Pharmaceutical Sciences

FRAMINGHAM RISK SCORE IN ESTIMATING CARDIOVASCULAR DISEASE RISK FACTORS IN PEOPLE OF ASIAN INDIAN ORIGIN: A STUDY ON RURAL ADULT POPULATION IN WEST BENGAL, INDIA

Tanmay Nag and Arnab Ghosh*

ABSTRACT

Aims: This study was aimed to investigate the efficacy of Framingham risk score (FRS) in estimating cardiovascular disease (CVD) risk in a rural adult population in West Bengal, India. Methods: This cross-sectional study was carried out among 1007 participants (645 males and 362 females) aged 20 to 80 years in a rural adult population in West Bengal, India. Anthropometric measures and blood pressure were collected using standard techniques. Metabolic profiles and insulin was also estimated and HOMA-IR was calculated subsequently. Results: The higher mean was observed for age, height, waist circumference, waist-hip ratio, total cholesterol, triglycerides, low and very low density lipoprotein cholesterol, fasting blood glucose, systolic and diastolic blood pressure and mean arterial pressure with increasing FRS category. On the contrary, lower mean was found for weight, hip circumference, waist-height ratio, body mass index, percentage body fat, sum of four skinfolds, high density lipoprotein cholesterol, insulin and insulin resistance. Significant age group difference was found in respect to FRS category. No remarkable difference was noticed in the prevalence of metabolic syndrome with increasing FRS. Conclusion: More comprehensive risk prediction algorithm is required to better comprehend the CVD and its’ risk factors in this population.

Keywords: FRS, CVD, type 2 diabetes, metabolic syndrome, Asian Indians.