A CONCISE REVIEW: CURRENT DEVELOPMENT AND FUTURE PROSPECTS OF PHARMACOLOGICAL ACTIVITIES OF LEUCAS ASPERA
Savitri U. Pathode*, Smita D. Lilhare, Yogesh K. Tirgam and Dr. Upadesh B. Lade
ABSTRACT
Leucas aspera, commonly known as "Thumbai" or "Dronapushpi," is a medicinal plant that has been traditionally
used in various cultures for its therapeutic properties. This review explores the current state of research on the
bioactive compounds derived from Leucas aspera and their potential applications in medicine. The plant is rich in
secondary metabolites such as alkaloids, flavonoids, terpenoids, and essential oils, which contribute to its diverse
pharmacological activities. Several studies have demonstrated the antioxidant, anti-inflammatory, antimicrobial,
and anticancer properties of Leucas aspera extracts. These bioactive compounds have shown promising results in
preclinical studies, indicating their potential for the development of novel therapeutic agents. Additionally, the
plant has been recognized for its traditional use in treating various ailments, including respiratory disorders, skin
diseases, and digestive issues. The review also highlights the ongoing efforts to isolate and characterize specific
bioactive compounds from Leucas aspera, providing insights into their molecular mechanisms and
pharmacokinetics. Furthermore, advancements in extraction techniques, formulation strategies, and
biotechnological approaches are discussed, aiming to enhance the bioavailability and efficacy of these compounds.
Looking toward the future, the review outlines potential directions for further research, emphasizing the need for
clinical trials to validate the safety and efficacy of Leucas aspera derived compounds in humans.
Keywords: Leucas aspera, Biocompounds, Pharmacological, Antimicrobial activity, Medicine.
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