European Journal of Biomedical and Pharmaceutical Sciences

ANTIHYPERLIPIDEMIC ACTIVITY OF SOME MEDICINAL PLANTS FROM BEKASI, WEST JAVA, INDONESIA - A REVIEW

Shabrina Zahratun Nisa, Adella Marsyanti, Aulia Nursyifa, Dhea Ananda, Diana Karlina,
Dini Hakiki, Fitrah Nurfitriani, Lutvia Ramadhina, Muhammad Rizki Aditya,
Nihal Shahifah, Putri Fitriyah Husnul Khotimah, Rifky Syarif, Ristin Prasmawati,
Rizma Septia Wahyuningsih, Tarradiva Rosita Fitri, and Maulana Yusuf Alkandahri*

ABSTRACT

Hyperlipidemia is a secondary metabolic dysregulation associated with increased levels of triglycerides, cholesterol, and LDL in serum which is a major risk factor for early cardiovascular diseases such as atherosclerosis, hypertension, coronary heart disease, and others. Increased plasma lipid levels, especially total cholesterol, triglycerides and LDL along with decreased HDL are known to cause hyperlipidemia which is the reason for the onset and development of atherosclerosis. Currently, researchers are starting to look for new antidyslipidemic compound candidates derived from natural ingredients that have been empirically proven to have antidyslipidemic effects. This is done to replace antihyperlipidemic drugs which currently have many side effects. Several medicinal plants native to Bekasi, Indonesia, including Moringa oleifera, Syzygium cumini, Aloe vera, Annona muricata, Persea americana, Curcuma longa, and Imperata cylindrica have been scientifically tested to have antihyperlipidemic activity with different mechanisms. Therefore, this review article will discuss the potential of several medicinal plants native to Bekasi, Indonesia which have effects as antidyslipidemia.

Keywords: Antihiperlipidemia, Medicinal plants Moringa oleifera, Syzygium cumini, Aloe vera, Annona muricata, Persea americana, Curcuma longa, Imperata cylindrica.