Abstract
AN OBSERVATIONAL PROSPECTIVE STUDY ON INDICATIONS FOR INTRAPARTUM ANTIBIOTICS AND THEIR EFFECTS ON NEONATAL OUTCOMES

Vandhana G*, Devapriya Vijayan, Lekshmi Gopal U, Dr. Akhila S Arjun, Dr. Chitra C Nair, Dr. Beena P

ABSTRACT

Aim: To identify the clinical indications for intrapartum antibiotic therapy and asess its impact on neonatal infections. Materials and Methods: A 6 months study were conducted in a teritiary care hospital in Kerala, India to analyze the indications for intrapartum antibiotics and their effect on neonatal outcomes of 75 pregnant women. Case records were prospectively reviewed and recorded in a specifically designed data collection form. Result: This study revealed a high occurrence of Gestational Diabetes Mellitus (GDM) and hypothyroidism among the study participants, further complicating the maternal-foetal outcomes. Conclusion: The study findings highlight about vigilant neonatal care and maternal factors that influence neonatal health. Clinical significance: Administration of intrapartum antibiotic prophylaxis (IAP) to pregnant women with GBS colonization can substantially reduce the early onset GBS disease and its further added complications.

Keywords: Neonatal infections, Intrapartum antibiotics, GDM, GBS disease, Hypothyroidism.


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