European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON IMPACT OF MICRO PLASTICS IN HUMAN BEINGS

B. Aswini*, F. Nishvanth and S. Shoba

ABSTRACT

Microplastics are ubiquitous in the global environment. As a typical emerging pollutant, their potential health hazards have become a significant concern. This brief paper introduces the sources, identification, toxicity, and health hazards of microplastics in humans. A review of the literature shows that microplastics are frequently detected in both environmental and human samples. Humans can be exposed to microplastics through oral intake, inhalation, and skin contact. We summarize the toxic effects of microplastics in experimental models, including cells, organoids, and animals. These effects include oxidative stress, DNA damage, organ dysfunction, metabolic disorders, immune responses, neurotoxicity, and reproductive and developmental toxicity. Additionally, epidemiological evidence suggests that a variety of chronic diseases may be related to microplastic exposure. Finally, we identify gaps in the toxicity research of microplastics and discuss their future development directions. This review will help improve the understanding of exposure risks and potential health hazards associated with microplastics.

Keywords: Micro plastics, Placenta, Infertility.