PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF BARK EXTRACT OF WRIGHTIA TINCTORIA AND COMPARATIVE STUDIES WITH AMOXICILLIN
J. Abishek*, V. Amoka, S. Anbuselvi, L. Anitha1, S. Banu, S. Arunvenkateshwaran, M. Manisha, Jothimanivannan C.
ABSTRACT
Plant extract have been used for a wide variety of purpose of many thousands of years. In particular the antimicrobial activity of plant extract has formed the basic of many application including raw and processed food preservation, pharmaceutical, alternative medicine and natural therapies. The bark of wrightia tinctoria is considered for anti-dirrhoeal, aphrodisiac,Anti-helmalit is febrifuge, stomachic,tooth ache,tonic. It has antibacterial, anti inflammatory, antioxidant, antifungal, anticancer, anti diabetes, antiviral activity. More over studies Pharmacognosy, antimicrobial activity and photochemistry part of wrightia tinctoria. Thebark of wrightia tinctoria contain bioactive compound such as alkaloids,saponins,quinine,tannins, glycosides,flavonoids, phenolic substance, terpenoids. It has antibacterial activity against both gram positive and gram negative studies have shown that extract from the bark effectively inhibit staphylococcus aureus and escherichia coli. The antimicrobial potential was assessed using the agar well diffusion method against bacteria. Among the different bacteria strains a more inhibitory action was observed against staphylococcus aureus and compare to standard drug amoxicillin.
Keywords: Wrightia Tinctoria, Anti Micriobial, Gram Positive, Anti inflammatory, Staphylococcus aureus, Escherichia Coli, Amoxicillin.
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