European Journal of Biomedical and Pharmaceutical Sciences

A PARTICLE-BASED FRAMEWORK FOR UNDERSTANDING THE ETIOLOGY OF AUTISM, ALZHEIMER’S, AND DEMENTIA: THE ROLE OF CONTAMINANTS IN NEUROTOXICITY

Eric Jesse Kikkert*

ABSTRACT

This article presents a theoretical framework grounded in physics to elucidate how contaminants, particularly heavy metals like aluminum, contribute to neurodevelopmental and neurodegenerative disorders. We focus primarily on autism as a condition arising from prenatal exposure to these toxins, which disrupt fetal brain development, and secondarily on how the same contaminants, when introduced to a fully developed brain, lead to Alzheimer’s disease (AD) and dementia, depending on the affected brain regions. By analyzing particle passage through biological barriers, their atomic interactions with brain tissues, and their impact on synaptic function, we propose a unified model of neurotoxicity. This work integrates Particle Progression as a particle model, providing physics-based insights through which the following can be defined: "physics makes your biology from scratch." We allow the factual evidence identified through physics to stand on its merits, offering a novel perspective for submission to a medical journal.

Keywords: Neurotoxicity, Autism, Alzheimer’s Disease, Dementia, Contaminants, Particle Physics