European Journal of Biomedical and Pharmaceutical Sciences

A PROSPECTIVE OBSERVATIONAL STUDY IN CARDIOVASCULAR RISK PROFILES IN CANCER PATIENTS

Raad Ali Kareem*, Hadi Badr Hasan and Nibras Naeemaha Jebur

ABSTRACT

This is a prospective cohort study involving 100 patients attending the oncology clinic from 2023 to 2024 that will enroll adult patients with a diagnosis of kidney cancer, colorectal cancer, hematologic tumors, or breast cancer who are scheduled to undergo chemotherapy. The main objective was to investigate cardiovascular risk, metabolic syndrome, and cardiovascular consequences, particularly DCRTC, related to systemic treatments (chemotherapy or targeted therapy) for various cancers, including lymphoma (DLBCL), chronic myeloid leukemia (CML), breast cancer, kidney cancer, and colorectal cancer. The cohort included 15 kidney cancer patients (15%; 4 women, 11 men), 25 with colorectal carcinoma (25%; 12 women, 13 men), 20 with hematological malignancies (20%; 12 women, 8 men), and the largest subgroup of 40 women with breast cancer (40%), The study found a difference between the subgroups with respect to age: patients with breast cancer were significantly younger than patients with colorectal cancer. In-conclusion: The observed cardiovascular consequences, particularly the development of DCRTC, it is crucial to implement regular cardiovascular assessments and preventive strategies in cancer treatment protocols.

Keywords: Cancer, DLBCL, myeloid leukemia, breast cancer.