PREVALENCE OF ANTIBIOTIC RESISTANCE IN A TERTIARY CARE HOSPITAL, AHMEDABAD
Dr. Vishwa Mehta*, Shubham Doriya, Samarpan Patel, Hetvi Mistry, Dr. Shruti D. Shah
ABSTRACT
Antimicrobial Resistance (AMR) arises when bacteria, viruses, fungi, and parasites develop resistance to
antimicrobial agents, rendering treatments ineffective and complicating infection management. This study aims to
examine the prevalence of antimicrobial resistance in Ahmedabad. A prospective cohort observational study was
conducted over six months in the inpatient ward, involving 1661 patients, following approval from the
Institutional Ethics Committee of GCS Medical College, Hospital & Research Centre. Patient Admitted or visiting
to the study facility with any disease during the study period were included, while those with isolated fungal
cultures were excluded. Statistical analysis involved mean, mode, and percentage. The predominant pathogens
observed in the sample include Klebsiella pneumoniae (33.77%), Pseudomonas aeruginosa (23.01%), and
Escherichia coli (21.46%). Coagulase-negative Staphylococcus exhibits complete resistance to several antibiotics,
including ampicillin, amoxicillin, ceftriaxone, ciprofloxacin, ofloxacin, erythromycin, azithromycin,
clarithromycin, tetracycline, doxycycline, and trimethoprim/sulfamethoxazole. This study concluded that
Antibiotic resistance is a growing global health crisis driven by the misuse and overuse of antibiotics. The
emergence of multidrug-resistant pathogens threatens the effectiveness of current treatments, leading to prolonged
illnesses, higher medical costs, and increased mortality.
Keywords: Antibiotics, Antimicrobial resistance, Penicillin, Cephalosporin and Klebsiella pneumonia.
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