European Journal of Biomedical and Pharmaceutical Sciences

ANTIOXIDANT ACTIVITY OF T-COLOSTROL, A SIDDHA PREPARATION MEANT FOR HYPOLIPIDEMIC AND CARDIOPROTECTIVE ACTIVITY

Veeraragavan M., Balwin Nambikkairaj, *Sivamani P., Dhayanithiy G.

ABSTRACT

Siddha medicine is one of the oldest medical systems known to mankind. Contemporary Tamil literature holds that the system of Siddha medicine originated in Southern India, in the state of Tamil Nadu. In this present study, a Siddha preparation called T-colostrol, known local hypolipidemic drug, containing a mixture of Musa paradisiaca stem juice, Black salt and Ferrous oxide was evaluated for its antioxidant activity in albino Wistar rats. Cholesterol powder, tween 80 and distilled water was given for induction. The present study proved that the antioxidant activity of T-Colostrol was effective to rats which showed increased catalase, SOD, Glutothione and decreased lipid peroxidase and also have DPPH scavenging activity. The results of T-colostrol are comparable to some extent with such drug. This study strongly suggests that the Siddha preparation could effectively be used as an antioxidant and a hypolipidemic therapeutic drug.

Keywords: Antioxidant activity, of T-colostrol, siddha preparation, hypolipidemic activity, cardioprotective activity.