Abstract
COMPARATIVE STUDY OF ANTHELMINTIC ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ALBIZIA LEBBECK LINN

Bhavana Madupoju*, Bhukya Nagaraju, Dr. Madireddy Mamata and R. Thirumuragan

ABSTRACT

Albizia lebbeck, commonly known as Indian Siris, is a versatile and esteemed medicinal plant with a rich history of traditional uses as anthelmintic bronchitis, asthma, eczema and allergic rhinitis etc. The present study is an attempt to explore the anthelmintic activity of aqueous and ethanolic extract of bark of plant Albizia lebbeck in a comparative study. The various doses of aqueous and ethanolic extracts were evaluated for their anthelmintic activities on adult Indian earthworms, Pheretima postuma. Both the solvent extracts were able to show anthelmintic activity at 10 mg/ml concentration. The activities are well comparable with the standard drugs, Piperazine citrate and Albendazole. All the doses of aqueous and ethanolic extract of Albizia lebbeck showed better anthelmintic activity than the standard drugs. When the dose of the extract is increased, a gradual increase in anthelmintic activity was observed. Aqueous extract showed better anthelmintic activity in comparison to the ethanolic extract of Albizia lebbeck. The data were verified as statistically significant by using one way ANOVA at 5 % level of significance (p < 0.05).

Keywords: Albizia lebbeck, Anthelmintic, Pheretima postuma, Standard drugs.


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