DUSHI VISHA AND CARCINOGENESIS: A CLINICAL AND EXPERIMENTAL REVIEW OF CHRONIC LOW-DOSE TOXIN EXPOSURE IN CANCER DEVELOPMENT
*Dr. Vyshnavi K. and Dr. Pradeep Patil
ABSTRACT
The escalating incidence of cancer worldwide has intensified the search for etiological factors beyond genetics and lifestyle, with a growing focus on chronic exposure to low-dose environmental toxins. Modern toxicology grapples with understanding the cumulative impact of these insidious poisons. Remarkably, the ancient Indian medical system of Ayurveda described a similar concept thousands of years ago known as Dushi Visha—a latent, cumulative poison that lingers in the body, causing chronic diseases over time. This article provides a clinical and experimental review of the Ayurvedic concept of Dushi Visha, drawing profound parallels with the modern understanding of chemical carcinogenesis. It explores the pathophysiology (Samprapti) of Dushi Visha, its clinical manifestations (Lakshanas), and its striking similarity to the multi-stage process of cancer development initiated by chronic, low-dose carcinogen exposure. By integrating classical Ayurvedic wisdom from texts like the Sushruta Samhita with contemporary scientific evidence, this review highlights the clinical importance of this ancient concept in preventive oncology and suggests an integrative therapeutic approach.
Keywords: Dushi Visha, Carcinogenesis, Ayurveda, Agada Tantra, Environmental Toxins, Chronic Toxicity, Integrative Oncology, Shodhana, Rasayana.
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