FORMULATION AND EVALUATION OF AN ELYTRARIA ACAULIS HERBAL OIL: PHYTOCHEMICAL PROFILE AND ANTI-INFLAMMATORY POTENTIAL
Balachandru Velmurugan, Prema Rathinam*, Senthil kumar Chelladurai, Chandrasekharan Padmanaban, Khalidha Banu Sheik Abdulla and Subalakshmi Thirupathi
ABSTRACT
The plant Elytraria acaulis belonging to the family Acanthaceae, also known as ‘Creeping foxglove’ is a small herb originated from peninsular India, but naturalized throughout the part of Southeast Asia and Tropical Africa and traditionally used in folk medicine for its anti-inflammatory, wound healing and antimicrobial properties. The plant grow close to the ground with a basal rosette of leaves and produces flower spikes directly from the soil. The purpose of this study is to provide comprehensive scientific information on the phytochemistry, traditional uses and anti- inflammatory properties of Elytraria acaulis Lindau (L.f). The leaves of the elytraria acaulis were subjected to soxhlet extraction using ethanol as solvent. The obtained extract was incorporated into seasame oil by the traditional method outlined in Indian pharmacopoeia. Preliminary phytochemical screening of the extract revealed the presence of alkaloids, flavonoids, tannins, glycosides many of which known for their anti-inflammatory properties. It is used to treat various ailments such as inflammation, skin disorder, and fever and body pain and also act as wound, healing enhancer. Elytraria acaulis oil has been used to treat anti- inflammation, bacterial disease and joint disorders. This study aims to explore the anti- inflammation properties by using phytochemical evaluation in- vitro by using protein Denaturation assay. The study also support the ethnomedicinal uses of the plant and encourages further pharmacological and clinical investigations.
Keywords: Elytraria acaulis Lindau, Phytochemical screening, Anti- inflammatory activity, Protein Denaturation Assay.
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