ROLE OF AMNIOTIC MEMBRANE IN ORAL AND MAXILLOFACIAL SURGERY: A REVIEW
*Saif Rauf Siddiqui, Nayef Abdulgani Alamer, Harjeet Singh Monga, Madhulika Srivastava, Sumbul Fatima
ABSTRACT
The amniotic membrane (AM) is considered an important potential source for scaffolding material. Amniotic
membrane is the inner most lining of the human placenta that is normally discarded after parturition and is
composed of a single epithelial layer, a thick basement membrane and an avascular stroma. The membrane has
numerous growth factors, proteins and stem cell reserves that help in accelerating wound healing with
regeneration of the lost tissues. In addition, the AM has other biological properties important for tissue
engineering, including anti-inflammatory, anti-microbial, anti-fibrosis, anti-scarring, as well as reasonable
mechanical property and low immunogenicity. The preserved human amniotic membrane is a novel tissue
engineered biomaterial that is recently tried in field of medicine and dentistry to regenerate the lost tissues and
accelerate repair. This review paper unfolds the inherent structure, properties, mechanisms and the applications of
this neglected tissue that makes it a potential material for regeneration especially in the field of oral and
maxillofacial surgeries.
Keywords: Amniotic membrane, Oral surgery, Dentistry.
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