THE MATERIAL THAT HEALS
K. Sreelatha*, C. S. Ananda Kumar1, C. A. Jyothirmayee2, V. Nagalakshmi3, M. Rama4, K. Swarnalatha5, N. Gayatri Devi6, P. Anusha7, N. Madhuri Rose8, Deepti Bhargav9, M. Tejaswi10, K. Triveni11
ABSTRACT
Bioactive glass has emerged as a transformative material in dental and biomedical sciences due to its ability to bond with living tissues and stimulate regeneration. First introduced in 1969, this innovative biomaterial exhibits exceptional bioactivity, biocompatibility, and antimicrobial properties. Upon exposure to physiological fluids, bioactive glass forms a hydroxyapatite layer, promoting osteointegration and dentinal repair. It has been successfully incorporated in a variety of applications, including bone grafts, implant coatings, dental restoratives, and oral care products. The material’s effectiveness in managing dentin hypersensitivity, preventing caries, and enhancing healing makes it indispensable in modern dentistry. Modifications involving ions like silver, strontium, zinc, and cobalt have expanded its functionality—improving angiogenesis, antibacterial action, and tissue regeneration. Injectable formulations and hydrogel-based bioactive glasses are being explored to improve adaptability and reduce brittleness. Glass ionomer cements, long considered passive materials, now incorporate bioactive components to offer remineralizing benefits. Bioactive glass not only ensures mechanical integrity but also promotes the physiological healing of hard and soft tissues. It plays a critical role in emerging fields like tissue engineering and regenerative dentistry. Future developments aim to optimize its composition for tailored therapeutic outcomes. With ongoing research, bioactive glass is poised to further redefine the standards of restorative and regenerative dental care.
Keywords: Bioactive Materials -Tissue Regenerative, Dental Restorative, Antibacterial.
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