European Journal of Biomedical and Pharmaceutical Sciences

FOURIER TRANSFORM INFRARED SPECTROSCOPIC (FT-IR) ANALYSIS OF SIDDHA FORMULATION – INGUSTATHY URUNDAI (IU)

R. Saradhadevi*, A. Muhilan, G. Essakky Pandian

ABSTRACT

The Siddha system of medicine, one of the oldest traditional medical systems of India, utilizes a wide range of formulations prepared from herbs, minerals, and animal products. Ingustathy Urundai (IU) is a classical Siddha formulation traditionally prescribed for Soothaga Vaayu (PCOS). Despite its extensive use, there is limited scientific validation regarding its composition and efficacy. In this study, FT-IR spectral analysis was performed to identify the functional groups and chemical nature of IU. The spectrum exhibited prominent peaks at 3405, 2925, 2854, 1641, 1511, 1456, 1363, 1113, 831, 617, and 548 cm⁻¹, indicating the presence of hydroxyl, carbonyl, aromatic, and metal–oxygen linkages. These findings confirm the coexistence of organic and inorganic constituents, validating the Siddha concept of synergistic therapeutic action. The results also suggest that the traditional preparation and purification processes effectively preserved the integrity of bioactive compounds. Overall, this study provides a scientific basis for the traditional claims of Ingustathy Urundai and supports its potential for further pharmacological and standardization studies.

Keywords: Siddha medicine, Ingustathy Urundai, FT-IR analysis, Soothaga Vaayu, functional group identification, quality evaluation.