European Journal of Biomedical and Pharmaceutical Sciences

ANNONA SQUAMOSA: A PROMISING MEDICINAL PLANT WITH DIVERSE PHARMACOLOGICAL ACTIVITIES – A REVIEW

*Poonam Ankush Jadhav (Asst. Proff.), Priyanka Sandip Sabale, Sanika Ajit Salvi,
Dipali Suresh Chormale (Lecturer)

ABSTRACT

Annona squamosa, commonly known as custard apple or sugar apple, is a tropical fruit-bearing plant belonging to the family Annonaceae. cultivated in the West Indies, South and Central America, Ecuador, Peru, Brazil, India, Mexico, the Bahamas, Bermuda, and Egypt. The leaves of Annona squamosa have been extensively studied for their health-promoting properties, which are attributed to a diverse array of phytochemicals. The fruit of this plant is commonly known as the custard apple, which is edible. Various parts of the tree have been used in traditional folkloric medicine. The pharmacological activities of Annona squamosa leaves are antimicrobial, antifungal, anti-inflammatory, anticancer, antiulcer, antidiabetic, antidiarrheal, antiplatelet, antioxidant, and hepatoprotective, neuroprotective, and cytoprotective. Powdered seeds are used to kill the head-lice and fleas, but care should be taken that the alkaloids, carbohydrates, fixed oils, tannins & phenolic compounds. It is related to contain alkaloids, carbohydrates, fixed oils, tannins & phenolic compounds. Traditionally, nearly every part of the plant—from the leaves and seeds to the bark and roots—has been used in folk medicine to treat ailments such as infections, inflammation, digestive issues, and parasitic infestations. Recent scientific studies are increasingly exploring Annona squamosa for its potential in modern medicine, especially for its promising anticancer and antimicrobial effects.

Keywords: Annona squamosa; biological activities; therapeutic applications; anti-ulcer.