“FROM ROOTS TO RHYTHM”: „SYNERGYSTIC ROLE OF ARJUNA TERMINALIA AND WITHANIA SOMNIFERA IN FORM OF POLYHERBAL CARDIOPROTECTIVE SYRUP?
*Poonam Ankush Jadhav (Asst. Proff.), Taher Unus Shaikh (Student), Dheeraj Jivan Sonkamble (Student),
Dipali Suresh Chormale (Lecturer)
ABSTRACT
In 2022, the World Health Organization (WHO) reported that cardiovascular diseases (CVDs) caused about 19.8 million deaths worldwide. These diseases affect the heart and blood vessels, including heart disease, stroke, blocked arteries, heart defects, and blood clots. Common risk factors for CVDs include diabetes, high blood pressure, and high cholesterol, lack of exercise, obesity, and tobacco and alcohol use. WHO estimated that India spent $237 billion on treating CVDs between 2005 and 2015. High blood pressure is strongly linked to heart disease, as it accelerates the build-up of plaque in arteries due to inflammation. Treatments often focus on lowering blood pressure to reduce this risk. Medications like β-blockers relax blood vessels and improve blood flow. High cholesterol also raises risk, and doctors treat it with drugs such as atorvastatin, though long-term use may increase the risk of type 2 diabetes. The bark of the Arjuna tree (Terminalia arjuna), found throughout India, contains natural compounds such as tannins, flavonoids, and minerals, which offer anti-inflammatory and anticancer benefits. Traditionally, Arjuna has been valued for heart health support, where modern therapies may rely on drugs with side effects. It has shown potential to lower blood sugar, prevent blood clots, reduce blood pressure, and fight infections. Its triterpenoids benefit the heart, while flavonoids and tannins target cancer, demonstrating a broader therapeutic profile than many standard medications.
Keywords: WHO estimated that India spent $237 billion on treating CVDs between 2005 and 2015.
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