European Journal of Biomedical and Pharmaceutical Sciences

INVESTIGATION OF THE PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL ACTIVITIES IN DATURA METEL.Linn

Karunakar T, Shankaraiah A. Parvathi.D and Ugandhar T.*

ABSTRACT

Medicinal plants are of great importance to the health of individuals and communities. A large number of plants are claimed to possess the anti-diabetic, anti-fertility, antihyperlipidaemic, anti-inflammatory, anti-cancer, hepatoprotective and immune modulatory activities in the traditional therapeutic systems. It is now believed that nature has given the cure of every disease in one way or another. Datura is known as a medicinal plant and plant hallucinogen all over the world. Datura has a very special place in Ayurveda since all parts of the plant namely leaves, flowers, seeds, roots, have been used for a wide range of medication such as treatment of leprosy, rabies, insanity, etc. The extract of Datura, however, is a potent poison and its indiscriminate use may lead to delirium and acute poisoning that may lead to death. The active constituents in Datura include scopolamine, atropine, hyoscyamine, withanolides (lactones) and other tropanes. The ethanolic extract of leaves of D.metal was investigated for its phytochemical properties and analysis for its active chemical ingredients. For qualitative and quantitative phytochemical analysis the ethanol extract of D.metal acts as a source of therapeutic agent.

Keywords: Datura metal chemical constituents, alkaloids, phytochemical screening, ethanol, extract, antidiabetic.