European Journal of Biomedical and Pharmaceutical Sciences

AYURVEDIC CDC MULTIMODAL PROTOCOL FOR TYPE 2 DIABETES MELLITUS AT MADHAVBAUG AMBERNATH CLINIC: GLYCAEMIC CONTROL, CARDIOMETABOLIC OUTCOMES AND ANTIDIABETIC DRUG REDUCTION IN 47 DM PACKAGE PATIENTS — A RETROSPECTIVE OBSERVATIONAL STUDY

Dr. Rohit Sane, Dr. Gurudatta Amin, Dr. Pravin Ghadigaonkar, Dr. Nilesh Kulthe*, Dr. Deepali Amin, Dr. Minal Kumbhare

ABSTRACT

Background: Ambernath, a rapidly urbanising town in Thane District, faces a growing burden of Type 2 diabetes mellitus (T2DM) driven by lifestyle changes, dietary transitions, and occupational stress. Madhavbaug's CDC (Chronic Disease Control) multimodal protocol integrates Panchakarma bio-purification, a low-carbohydrate Prameha Diet Box, and individualised herbal medication as a structured Ayurvedic intervention for T2DM. This retrospective study presents the first clinic-specific outcomes analysis exclusively from the Madhavbaug Ambernath clinic DM Package patients. Objective: To evaluate the effect of the Madhavbaug CDC Panchakarma-based multimodal protocol on glycaemic, anthropometric, haemodynamic, and cardiometabolic parameters, and antidiabetic medication reduction, in 47 DM Package patients at the Ambernath Central RIC clinic. Methods: Retrospective observational study. 47 patients with Type 2 diabetes mellitus enrolled exclusively in the DM Package (CDC-SP Base, CDC-SP 1, CDC-SP 2, CDC-KP Base) at Madhavbaug Ambernath clinic. Parameters analysed: HbA1c, RBS, weight, BMI, abdominal girth, SBP, DBP, heart rate, total cholesterol, triglycerides, LDL, HDL. Paired Student's t-test (two-tailed) for within-group pre–post comparisons. Significance threshold: p<0.05. Results: Highly significant improvements were observed in both primary glycaemic outcomes: HbA1c declined from 8.87±2.23% to 7.50±1.97% (Δ −1.37%, −15.5%, p<0.001, n=41); RBS reduced from 251.68±91.47 to 197.75±95.99 mg/dL (Δ −53.93 mg/dL, −21.4%, p<0.001, n=44). Significant improvements were also recorded in weight (−3.19 kg, −4.6%, p=0.006), abdominal girth (−2.68 cm, −2.8%, p<0.001), SBP (−5.45 mmHg, −4.2%, p=0.008), DBP (−3.57 mmHg, −4.2%, p=0.025), and heart rate (−3.77 bpm, −4.2%, p=0.017). Total cholesterol fell by 20.8% (p=0.028) and triglycerides by 36.8% (p=0.032) in the lipid-documented subgroup. Antidiabetic medication reduction was achieved in 21.3% of patients (10/47), including 1 complete cessation. Conclusion: The Madhavbaug CDC DM Package at Ambernath clinic achieved statistically significant improvements across primary glycaemic (HbA1c, RBS), anthropometric (weight, abdominal girth), haemodynamic (SBP, DBP, heart rate), and lipid parameters in 47 T2DM patients. These findings provide robust clinic-specific evidence for the integrative Ayurvedic protocol's effectiveness in the Ambernath diabetic population.

Keywords: Ambernath, Type 2 diabetes mellitus, HbA1c, CDC protocol, Panchakarma, Ayurveda, RBS, blood pressure, BMI, abdominal girth, antidiabetic drug reduction, glycaemic control, cardiometabolic, retrospective.