Abstract
COMPARATIVE EVALUATION OF BLOOD SUGAR VARIATIONS IN DIABETIC AND NON-DIABETIC CHRONIC KIDNEY FAILURE PATIENTS UNDERGOING MAINTENANCE HEMODIALYSIS

Augustar Dkhar*, Ms. Ibtisam Nazir Khan, Dr. Amandeep Singh

ABSTRACT

Background: Hemodialysis influences glucose metabolism and may cause significant fluctuations in blood sugar levels, particularly among diabetic patients with chronic kidney disease. Monitoring glycemic changes during dialysis is important for preventing metabolic complications and improving patient outcomes. Objectives: To evaluate and compare pre- and post-dialytic blood sugar levels among diabetic and non-diabetic patients undergoing maintenance hemodialysis. Methods: A hospital-based observational study was conducted on 50 patients undergoing maintenance hemodialysis. Patients were categorized into diabetic (n=35) and non-diabetic (n=15) groups. Demographic variables including gender, age, dialysis vintage, and diabetic status were recorded. Blood sugar levels were assessed before and after hemodialysis sessions. Data were analyzed using appropriate statistical methods, and significance was considered at p<0.05. Results: Among the 50 participants, 54.00% were females and 46.00% were males. The majority of patients belonged to the 51–60 years age group (28.00%). Most patients (56.00%) had a dialysis vintage of 1–5 years, while 70.00% were diabetic. In diabetic patients, mean blood sugar levels significantly decreased from 201.68 ± 25.27 mg/dL pre-dialysis to 155.50 ± 19.88 mg/dL post-dialysis. In non-diabetic patients, blood sugar levels decreased from 99.80 ± 3.00 mg/dL to 89.53 ± 2.33 mg/dL following dialysis. The difference was statistically significant (F=168.366; p=0.001). Conclusion: Hemodialysis significantly reduces blood sugar levels in both diabetic and non-diabetic patients, with a greater reduction observed among diabetic individuals. Regular monitoring of blood glucose during dialysis is essential to prevent glycemic complications and ensure safe clinical management of patients undergoing maintenance hemodialysis.

Keywords: Hemodialysis, Blood sugar level, Diabetes mellitus, Chronic kidney disease, Dialysis patients.


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