European Journal of Biomedical and Pharmaceutical Sciences

A COMPLETE REVIEW ON ADVANCEMENTS IN TRANSDERMAL PATCH TECHNOLOGY FOR PAIN MANAGEMENT AND HORMONE DELIVERY

Bikram Sarkar, Pritha Singha Roy, Ankush Biswas, Sourav Chakraborty, Bipul Sarkar*

ABSTRACT

Recent advancements in transdermal patch technology have transformed the landscape of pain management and hormone delivery, offering non-invasive and convenient options for patients. These patches deliver medications and hormones through the skin, bypassing the gastrointestinal tract and liver metabolism, thereby minimizing systemic side effects and enhancing patient compliance. In pain management, transdermal patches now employ sophisticated mechanisms for controlled and sustained drug release. Utilizing permeation enhancers, matrix systems, and reservoir technologies, these patches ensure consistent pain relief over extended durations. Formulations with nano- and microparticles enable targeted delivery to specific pain sites, optimizing efficacy while minimizing systemic exposure. Additionally, wearable technology integration facilitates real-time monitoring of medication adherence and physiological responses, enhancing treatment outcomes. Similarly, transdermal hormone delivery systems have seen significant progress. Advanced patch designs, including microstructured arrays and iontophoresis, enhance hormone permeation, ensuring optimal bioavailability and pharmacokinetics. Biocompatible polymers and biodegradable materials minimize skin irritation, improving patient comfort during long-term therapy. Wearable sensors enable personalized dosing schedules and real-time monitoring, empowering patients and healthcare providers alike. In summary, recent innovations in transdermal patch technology offer improved efficacy, convenience, and patient satisfaction in pain management and hormone delivery. These advancements, coupled with wearable technology integration, hold promise for personalized therapy and enhanced treatment outcomes. Continued research and innovation in this field are poised to further revolutionize patient care for chronic pain and hormonal imbalances.

Keywords: Transdermal patch, Hormone delivery, Permeation enhancers, Wearable technology, Controlled delivery, Biocompatible polymers.