A COMPREHENSIVE REVIEW ON THE THERAPEUTIC ROLE OF CORTICOSTEROIDS IN DERMATOLOGICAL DISEASE MANAGEMENT
Ms. Malavika P U*, Dr. S. Aravinth Vijay Jesuraj
ABSTRACT
Skin diseases represent a significant global health burden, affecting millions of individuals and contributing substantially to morbidity and reduced quality of life. Common dermatological conditions such as psoriasis, atopic dermatitis, seborrheic dermatitis, contact dermatitis, acne vulgaris, and vitiligo are largely driven by inflammatory and immune-mediated mechanisms. Among available therapeutic options, corticosteroids remain a cornerstone in dermatological practice due to their potent anti-inflammatory and immunosuppressive properties. This review provides a comprehensive overview of the role of corticosteroids in the management of various skin disorders, focusing on their mechanisms of action, clinical applications, pharmacokinetics, pharmacodynamics, and classification. It also highlights appropriate prescribing practices, including selection of potency, duration of therapy, and methods to enhance patient adherence while minimizing adverse effects. Special emphasis is placed on safety concerns associated with prolonged or inappropriate use, such as local skin changes and systemic complications. This review aims to provide a comprehensive overview of the therapeutic effectiveness, clinical applications, safety considerations in corticosteroid therapy for dermatological conditions.
Keywords: Topical corticosteroids, Skin diseases, Dermatology, Inflammation, Psoriasis and Atopic dermatitis.
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