Abstract
REVIEW ON SIDDHA MEDICINAL PLANTS AND FORMULATIONS WITH THROMBOLYTIC ACTIVITY

Vidhya Somasundaram*, Ramani Mani, Tamil Muhil Mathavan Kaarthikeyan, Saravana Singh Karan, Chand Mohan Singh

ABSTRACT

Thrombotic diseases myocardial infarction or cerebral infarction is serious consequences of the thrombus formed in blood vessels. Thrombolytics are the drugs to lyse thrombi to recanalize occluded blood vessels. Commonly used thrombolytics are Streptokinase, Urokinase, tissue Plasminogen Activator to dissolve the clots. Currently available thrombolytic agents still have significant shortcomings, including the need for large dose to be maximally effective, limited fibrin specificity & bleeding tendency. These shortcomings present in thrombolytic agents have started to seek the attractive alternative medicines. Siddha have huge source of medicine for various diseases. They mention the different properties of Herbal, Mineral and Herbo – mineral drugs which can be used in different disease by making many combination and formulation. This present review had as its objective the compiling of data based on works carried out in some Siddha Medicinal plants that are consumed frequently by humans & that have demonstrated thrombolytic activity.

Keywords: Thrombotic diseases, Thrombolytic activity, Thrombolytics, Siddha Medicinal plants.


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