A STUDY ON PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT POTENTIALS OF PLANTS USED IN THE TREATMENT OF VITILIGO
Jayarama Reddy* Ranganathan.T.V and Jeldi Hemachandran
ABSTRACT
Vitiligo is an acquired disorder of pigmentation, caused by decreased
production of melanin as a result of dysfunction of melanocytes.
Antioxidants are compounds that help to inhibit many oxidation
reactions caused by free radicals such as singlet oxygen, superoxide,
peroxyl radicals, hydroxyl radicals etc, there by preventing or delaying
the damage to the cells and tissues. Plant derived natural products such
as flavonoids, terpenoids and steroids etc have diverse pharmacological properties including
antioxidant activity. The present work antioxidant potentials of some medicinal plants were
used in treatment of Vitiligo. Cassia fistula, Eclipta alba, Plumbago zeylanica, Lawsonia
inermis, and Indigofera tinctoria were used in this investigation as they are known to be
having antioxidant properties. The methanolic and aqueous extracts of all four plants were
investigated. It revealed the presence of phenols, flavonoids, tannins, alkaloids, terpenoids
and steroids in the extracts. Reducing power was also high in aqueous extract. The results of
this study show that the aqueous extract of all the plants studied can be used as easily
accessible source of natural antioxidants in the treatment of Vitiligo.
Keywords: Vitiligo, antioxidants, plant extracts, phytochemical analysis.
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