Abstract
A STUDY ON PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT POTENTIALS OF PLANTS USED IN THE TREATMENT OF VITILIGO

Jayarama Reddy* Ranganathan.T.V and Jeldi Hemachandran

ABSTRACT

Vitiligo is an acquired disorder of pigmentation, caused by decreased production of melanin as a result of dysfunction of melanocytes. Antioxidants are compounds that help to inhibit many oxidation reactions caused by free radicals such as singlet oxygen, superoxide, peroxyl radicals, hydroxyl radicals etc, there by preventing or delaying the damage to the cells and tissues. Plant derived natural products such as flavonoids, terpenoids and steroids etc have diverse pharmacological properties including antioxidant activity. The present work antioxidant potentials of some medicinal plants were used in treatment of Vitiligo. Cassia fistula, Eclipta alba, Plumbago zeylanica, Lawsonia inermis, and Indigofera tinctoria were used in this investigation as they are known to be having antioxidant properties. The methanolic and aqueous extracts of all four plants were investigated. It revealed the presence of phenols, flavonoids, tannins, alkaloids, terpenoids and steroids in the extracts. Reducing power was also high in aqueous extract. The results of this study show that the aqueous extract of all the plants studied can be used as easily accessible source of natural antioxidants in the treatment of Vitiligo.

Keywords: Vitiligo, antioxidants, plant extracts, phytochemical analysis.


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