Abstract
EFFECT OF PROCESS PARAMETERS ON DESIGN OF VESICULAR SYSTEMS CARRYING ACECLOFENAC

Prachi Pandey* and S.S. Pancholi

ABSTRACT

The Vesicular carrier based drug delivery systems are a recent breakthrough to achieve target specificity and minimization of adverse effects associated with drug. Inspite of such novelty associated, carrier systems suffer from drawback like non-uniformity in size. The present study is based on determination of optimum process conditions to obtain vesicles of uniform size carrying drug Aceclofenac. The results indicate a strong influence of temperature, time and rotations per minute of rotary evaporator and sonication cycles, amplitude and time on the size of Liposomes and transferosomes prepared using lipids and surfactants.

Keywords: Nanocarriers, size, Process optimization.


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