Abstract
A COMPARATIVE STUDY BETWEEN LABETALOL AND METHYLDOPA IN MANAGEMENT OF PREECLAMPSIA IN A TERITIARY CARE TEACHING HOSPITAL

* Dr. T. Lakshmi Suseela, Dr. S. Jaya Jyothi, Dr.T. Mahendra, Dr. S Parveen

ABSTRACT

Preeclampsia complicates 3 to 10% of pregnancies in primigravida and is variable and less in multipara. It is the second common cause for maternal morbidity, mortality and iatrogenic preterm deliveries. To compare the efficacy and safety of labetalol versus Methyldopa in the management of preeclampsia. The study was conducted in Rajiv Gandhi Institute of Medical Sciences, Kadapa for 2 years (2013-2015) on 100 pregnant women with preeclampsia were randomly assigned, 50 were treated with two different anti-hypertensives Labetalol (Group A) and 50 with Methyldopa (Group B) randomly with matching distribution. The results shown that Labetalol is effective & early onset of action with fewer side effects compared to Methyldopa on the study patients. The chances of spontaneous onset of labor was greater, those who were induced had better Bishops score. On concluding the study, Labetalol is safe, quicker control of blood pressure and lesser side effects and thus advantageous over Methyldopa in the management of preeclampsia.

Keywords: Preeclampsia, Labetalol, Methyldopa.


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