Abstract
QUALITY ASSESSMENT FOR TWO YEMENI GLIMIPRIDE BRANDS COMPARED TO THE ORIGINAL BRAND

Wafa Al-Madhagi*, Ahmed Abdulbari Ahmed Albarakani, Abobakr Khaled Alhag, Zakaria Ahmed Saeed, Nahlah Mansour Noman and Khaldon Mohamed

ABSTRACT

The aim of the present study is to evaluate the effectiveness of Yemeni glimepride tablets in compare with amaryl 3mg as a reference drug. As result of this, this research would concern about evaluation of the Yemeni glimiperide (brand A and Glimaryl) in order to increase the Yemeni products to be competitive to amaryl the reference drug. According to quality control tests the brand A gave the minimum disintegration time but the tablets was friable so the hardness test were rejected as well as the weight variation. The hardness of brand gave significant difference with Amaryl that make the product is not accepted. The Glimaryl showed non-significant difference with Amaryl and close weight and weight variation. Glimaryl can be best alternative and comparative to the Amaryl.

Keywords: glimipride, quality control, Yemeni glimipride.


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