Abstract
MONITORING AND REPORTED THE ADVERSE DRUG REACTIONS OF DIFFERENT DRUGS IN RURAL GOVERNAMENT HOSPITAL IN NALGONDA SPONTANEOUS REPORTING METHOD

N. Shiva Krishna*, K. Nava Jyothi, H. Ramana, M. Rajeshwari1, B. Rajini, Y. Ashwini, K. Lakshmi Surekha, G. Venkateshwarlu and B. Shankar, M. Sai

ABSTRACT

Adverse drug reactions (ADRs) are one of the major problems associated with medicines. The effectiveness and success of any pharmacovigilance system depends highly on the participation of all health care professionals. An observational, prospective study was conducted based on ADRs reported between Feb 2nd to 18 th march to the ADR reporting unit of the hospital. The ADRs reported by spontaneous reporting system were from patients attending in-patient department (IPD) and casualty of IGGMC&H Nalgonda Evaluation of the data was done for various parameters which included patient demographics, drug and reaction characteristics, and outcome of the reactions. Assessment was also done for causality and severity. Total 75 ADRs were reported with in the period from 2nd Feb. to 18th March. Cefrioxome were the drug class most commonly involved and next Cefixime a well established agent was the individual drug most frequently reported in this study. Upon causality assessment, majority of the reports were rated as probable (13.043%). The pattern of ADRs reported in our hospital is comparable with the results of studies conducted in hospital set up elsewhere. Cefrioxome were causing maximum ADRs. This study provides a database of ADRs due to common drugs used in our hospital, which will help clinicians for optimum and safe use of these drugs. Hence strict vigilance is required for the use of these likely drugs and their safety assessment.

Keywords: adverse drug reactions, hospital based monitoring, pharmacovigilance, survey of patients.


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