Abstract
PROTECTIVE ROLE OF RUTIN ON PACLITAXEL-INDUCED LIPID PEROXIDATIO

Supratim Ray*

ABSTRACT

Considering drug induced lipid peroxidation as a possible mediator of drug induced toxicity and exploiting the free radical scavenging activity of antioxidant, the present study was designed to evaluate the free radical scavenging activity rutin on paclitaxel-induced lipid peroxidation. This in vitro work was carried out with goat liver as lipid source using malondialdehyde and 4-hydroxy-2-nonenal as model markers. The findings suggest that paclitaxel could induce lipid peroxidation to a significant extent and it was also found that rutin has the ability to suppress the paclitaxel-induced toxicity.

Keywords: Paclitaxel, rutin, lipid peroxidation, malondialdehyde, 4-hydroxy-2-nonenal.


[Full Text Article]   [Download Certificate]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: MARCH ISSUE PUBLISHED

    MARCH 2024 Issue has been successfully launched on 1 MARCH 2024.

  • EJBPS New Impact Factor

    EJBPS Impact Factor has been Increased to 7.482 for Year 2024.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT