PHARMACEUTICAL EVALUATION OF MUSTA-TRIPHALADI AVALEHA, AN AYURVEDIC POLYHERBAL FORMULATION
O.T.M.R.K.S.B. Kalawana*, Patel K.S., Rajagopala S., Kori V.K. and Shukla V.J.
ABSTRACT
According to the ayurvedic perspective properties and the action of the drug is described with their rasa panchaka.
And also ancient ayurvedic aachaaryas have mentioned various methods to quality control and to standardization
the ayurvedic formulations. But in the present scientific era it is a necessity to explain ayuervedic fundamentals
also in modern scientific manner for the comprehensive acceptance. Hence present study was carried out to ensure
the quality standards of the formulation, Musta-triphaladi Avaleha with preliminary physico-chemical parameters
and pharmaceutical characteristics. This is a modified ayurvedic formulation which is used in the management of
Thalassemia Major. Avaleha is a herbal drug compound prepared in dosage format of a semi-solid consistency of
the drugs meant for licking (lincture) and has been tried clinically as an adjuvant with proven results. The test drug
was prepared in the Pharmacy, G.A.U., Jamnagar. Analytical study of test drug was carried out at pharmaceutical
laboratory, I.P.G.T. & R.A., Jamnagar. In the pharmaceutical study, it was observed that Loss on drying was
11.094% w/w, pH was 6.0, Water soluble extractive was 76.29% w/w, Alcohol soluble extractive was 83.65%
w/w, Ash Value was 0.142 g and Acid insoluble Ash was 0.193% w/w. And also presence of Carbohydrate,
Tannins and Phenolic Compounds and Steroid were observed. In HPTLC study 09 peaks at 254 nm and 08 peaks
at 366 nm wave lengths were indicated.
Keywords: Musta-triphaladi Avaleha, l, Physico-Chemical, Thalassemia Major.
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