Abstract
PREVALENCE OF THYROID DYSFUNCTION AMONG THE ADULT POPULATION OF KANCHIPURAM DISTRICT, TAMILNADU

P. Modagan*, Dr. A. Renuka, Dr. A. Manamalli and Dr. Santhi Silambanan

ABSTRACT

Background: Thyroid disease is common worldwide and in India it is a major health issue in female adult population. Thyroid hormone regulates several metabolic process of the body, various functional or structural disorders of which lead to hypothyroidism. The severity depends on the degree and duration of thyroid hormone deprivation. It represents a wide-range and often nonspecific symptoms so needs to be considered in many differentials and once diagnosed, needs to be regularly monitored to optimise therapy. Therefore initial clinical assessment and laboratory testing would provide a better diagnosis when thyroid dysfunction is suspected to minimize further complications. Objective: To establish the prevalence of thyroid disease in adult population of Kanchipuram district, TamilNadu. Materials and Methods: 1306 subjects, who attended the outpatient department of Sri Muthukumaran Medical College Hospital and Research Institute, Chennai for hormonal evaluation during the period of 2014 to 2015, were assessed for thyroid function test by Enzyme Linked Florescent Immunoassay (ELFA) with Mini-Vidas Auto analyzer. Results: Among the 1306 subjects, thyroid dysfunction was found in 35.83% (468) patients and 64.16% (838) had euthyroid. Out of 468 cases, 81.83% of patients were hypothyroid and 18.16% had hyperthyroid. There was significant difference in thyroid hormone levels (p< 0.0001) in hypothyroid and hyperthyroid as compared with euthyroid subjects. A high prevalence of hypothyroidism and hyperthyroidism was observed in the age group of 20 to 35 and 36 to 50 years respectively. Conclusion: Thyroid dysfunction by itself can cause various health related problems and can also affect the health and quality of life. Therefore routine screening during master health checkup program may be helpful in identifying individuals with thyroid dysfunction.

Keywords: Hypothyroidism, Hyperthyroidism, Enzyme linked florescent immunoassay.


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