PREVALENCE OF THYROID DYSFUNCTION AMONG THE ADULT POPULATION OF KANCHIPURAM DISTRICT, TAMILNADU
P. Modagan*, Dr. A. Renuka, Dr. A. Manamalli and Dr. Santhi Silambanan
ABSTRACT
Background: Thyroid disease is common worldwide and in India it is a major health issue in female adult
population. Thyroid hormone regulates several metabolic process of the body, various functional or structural
disorders of which lead to hypothyroidism. The severity depends on the degree and duration of thyroid hormone
deprivation. It represents a wide-range and often nonspecific symptoms so
needs to be considered in many
differentials and once diagnosed, needs to be regularly monitored to optimise therapy. Therefore initial clinical
assessment and laboratory testing would provide a better diagnosis when thyroid dysfunction is suspected to
minimize further complications. Objective: To establish the prevalence of thyroid disease in adult population of
Kanchipuram district, TamilNadu. Materials and Methods: 1306 subjects, who attended the outpatient
department of Sri Muthukumaran Medical College Hospital and Research Institute, Chennai for hormonal
evaluation during the period of 2014 to 2015, were assessed for thyroid function test by Enzyme Linked
Florescent Immunoassay (ELFA) with Mini-Vidas Auto analyzer. Results: Among the 1306 subjects, thyroid
dysfunction was found in 35.83% (468) patients and 64.16% (838) had euthyroid. Out of 468 cases, 81.83% of
patients were hypothyroid and 18.16% had hyperthyroid. There was significant difference in thyroid hormone
levels (p< 0.0001) in hypothyroid and hyperthyroid as compared with euthyroid subjects. A high prevalence of
hypothyroidism and hyperthyroidism was observed in the age group of 20 to 35 and 36 to 50 years respectively.
Conclusion: Thyroid dysfunction by itself can cause various health related problems and can also affect the health
and quality of life. Therefore routine screening during master health checkup program may be helpful in
identifying individuals with thyroid dysfunction.
Keywords: Hypothyroidism, Hyperthyroidism, Enzyme linked florescent immunoassay.
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