European Journal of Biomedical and Pharmaceutical Sciences

COMPARATIVE IN VITRO ANTIMICROBIAL ACTIVITY OF ELETTARIA CARDAMOMUM FRUIT AND MENTHA SPICATA LEAVES

Almoeiz Y. Hammad*, Sabah E.A.Eltegani and Warda S. Abdelgadir

ABSTRACT

The study aim was to evaluate the antibacterial activities of E. Cardamomum and Mentha spicata N. hexane, methanolic and aqueous extracts. Antibacterial property of plant extracts were evaluated using disc diffusion technique against two Gram positive bacteria (Staphylococcus aureus and Bacillus subtilis), three Gram negative bacteria (Escherichia coli - Pseudomonas aeruginosa and Salmonella typhi) and one fungi (Candida albicans). The results showed that all the test organisms including C. albicans were resistant to the methanolic and aqueous extracts. Except Pseudomonas aeruginosa, the rest of test organisms were sensitive to n-Hexane extract with C.albicans being the most sensitive. The methanolic extract of Menth spicata was the most active inhibiting all the test organisms except Pseudomonas aeruginosa which is again resistant to this extract but C. albicans being the most sensitive. It was also found that E. coli was sensitive to both n-Hexane and aqueous extracts.

Keywords: Elettaria Cardamomum, Mentha spicata, antimicrobial activity, N.hexane, methanol, water.