STUDY OF THE ACTIVITY OF SALIVARY ALKALINE PHOSPHATASE, CONCENTRATION OF SALIVARY CALCIUM AND PHOSPHOROUS IN DENTAL CARIES
Dr. Arshiya Jadhav*, Dr. S. P. Dhonde, Dr. P. E. Jagtap, Dr. Anand Shigli, Dr. G. J. Belwalkar, Dr. N. S. Nagane
ABSTRACT
Introduction – The minerals calcium and phosphorous from saliva, along with the enzyme salivary alkaline phosphatase plays an important role in the mineralization of the teeth. Dental caries is characterized by demineralization of the inorganic portion and destruction of the organic substances of the tooth which often leads to cavities. Aims and Objectives - To evaluate the activities of salivary alkaline phosphatase, and concentration of salivary calcium, phosphorous in dental caries. Material and Methods – Salivary calcium, phosphorous, alkaline phosphatase from stimulated saliva of 135 subjects with dental caries and 135 caries free Individuals, were analyzed with automated biochemistry analyzer – Corolyzer. Results – Data analysis revealed significantly decreased concentration of salivary calcium, phosphorous along with significantly increased activity of alkaline phosphatase. Conclusion –Stimulated saliva contains more amount of bicarbonate, it increases the pH of the saliva. This change in pH favours activity of alkaline phosphatase. Augmented activity of salivary alkaline phosphatase may promote the process of remineralization. This remineralization process utilizes calcium and phosphorous from the saliva for deposition on enamel, and may result into decreased concentration of these minerals in the saliva of study group.
Keywords: Salivary alkaline phosphatase, calcium, phosphorous, dental caries.
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