European Journal of Biomedical and Pharmaceutical Sciences

THE STATUS OF SERUM LIPID PROFILE IN STRESS-RELATED PRE-INSOMNIA

Uba A.I1,*, Abdullahi I.L, Abdullahi, S.A and Adamu H

ABSTRACT

Understanding of the correlation between stress, pre-insomnia and serum lipid profile status may provide clues toward the management of stress- related cardiovascular diseases. This study assessed the serum lipid profile on a total of thirty seven (37) male and female subjects; twenty eight (28) of which are students selected from different departments and nine (9), within Kano city. Twenty five (25) served as experimental subjects and twelve (12) as control subjects. Their blood pressure was taken and information on general life style, sleeping as well as reading habits was recorded by means of well-structured questionnaire prior to sample collection. Venous blood (5ml) was collected from each subject, centrifuged and the sera stored. Serum lipid profile was assayed using commercial kit from fortress diagnostics limited. When the Mean serum Total Cholesterol, High Density Lipoprotein Cholesterol, Low Density Lipoprotein Cholesterol and Triglyceride levels of test subjects were compared with those of the control subjects the difference was not significant (p˃0.05). When comparison was made within the study group, based on borderline risk of high and normal blood pressure, the serum lipid profile level was found to differ significantly (p˂0.05). Thus our study showed that acute sleep deprivation (pre-insomnia) does not alter serum lipid profile, however, is associated with mild hypertension which is a risk factor for cardiovascular diseases.

Keywords: Pre-insomnia, Stress, Lipid profile.