THE CORRELATION BETWEEN THE BLOOD AND HORMONAL DISORDERS WITH SYNDROME OF POLYCYSTIC OVARIES IN WOMEN OF THE BAGHDAD CITY
Inaam Noori Ali*, Mustafa A. J. Alhiti and Hayder Ghassan Jawad
ABSTRACT
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder affecting around 8-10% of women characterized mainly by hyperandrogenism and chronic anovulation associated with other variable manifestations such as insulin resistance, dyslipidemia and hirsutism. Thirty female patients with PCOS together with twenty healthy volunteer females included as controls. Serum levels of hormones such as FSH, LH, testosterone and prolactin were tested in the two groups. Blood parameters (RBC count, WBC count, PCV, Hb, platelet count, MCV, MCHC and RDW were evaluated in this study in addition to the estimate the correlation between blood parameters and hormonal level be a part of the correlation. Hormonal parameters of patients of PCOS showed a statistically highly significant (P < 0.0001) decrease in follicular stimulating hormone (FSH) levels (4.01± 0.33) compared to control group (6.91 ± 0.35) whereas the luteinizing hormone (LH) of patients showed highly significant increase (P < 0.0001) in their level (11.56 ± 0.60) as compared with control group(3.86 ± 0.38). The statistical analysis of results for blood parameters showed that there is highly significant difference (P < 0.0001)in WBC, RBC, Hb, MCV, MCH, MCHC, RDW-CV and platelet for PCOS patients when compared with control group. an intermediate positive correlation and significantly difference (P < 0.05) was found between WBC count and testosterone level in the blood of PCOS patients group, meanwhile a strong positive correlation and highly significant difference (P < 0.01) was found between the RBC count and testosterone level (r=0.47).
Keywords: PCOS, Blood parameters, hormonal parameters, Baghdad city.
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