European Journal of Biomedical and Pharmaceutical Sciences

CARDIOMYOPATHY COMPLICATING PREGNANCY. OUTCOME OF 25 CASES AND REVIEW OF LITERATURE.

Dr. Latika Sahu*, Dr. Reena Rani and Dr. Asmita M. Rathore

ABSTRACT

Background: Cardiomyopathy associated with pregnancy is very rare. It can be a peripartum cardiomyopathy or other varieties like dilated and hypertrophic cardiomyopathy which either develop during pregnancy or they were existent before pregnancy. Though the incidence is very low the mortality rates and morbidity associated with this condition is very high during pregnancy. Material and methods: Data of 25 cases of cardiomyopathy complicating pregnancy collected in a period of 2 year duration associated with pregnancy and reviewed for clinical profile, maternal and peinatal outcome, associated etiological factor, the management and course of the disease of the women were recorded. Result: Mean age of the patients was- 25.92±3.22year. Commonly associated conditions were hypertension (36%), anaemia (24%). Nineteen out of 25 cases were diagnosed to be peripartum cardiomyopathy (PPCM) and 6 cases were diagnosed to be dilated cardiomyopathy (DCMP). The left ventricular ejection fraction of the patients at the time of diagnosis/ at the time of admission was 31.33±8.11 (mean ± SD) and improved during hospital stay at the time of discharge up to (45%). Maternal mortality rate was 8%. Conclusion: This study tries to define the clinical profile, maternal and perinatal outcomes of the pregnant women with pre-existing and peripartum cardiomyopathy.

Keywords: Cardiomyopathy associated with pregnancy is very rare.