European Journal of Biomedical and Pharmaceutical Sciences

A SYNOPSIS ON TORCH SYNDROME DURING PREGNANCY

Essa Ajmi Alodeani, Mohammad Asrar Izhari*, Mohammad Arshad* Sanjay Deshwali, Bader Metlee Al-Ruwies, Doaa Mohamed Sheriff Ali

ABSTRACT

The prenatal and perinatal torch infections in women and neonates raise global concern because of their worldwide occurrence and higher degree of prevalence. Primary infections arises due to these viruses leads to bad obstetric history and it is also a matter of concern to identify and have the knowledge about the pathogen associated with clinical disease in patient having infections. The infection caused by Rubella virus leads to birth defects such as blindness, hearing defects, and mental problem. While similar manifestations possessed by CMV. Herpes simplex virus (HSV) HSV may lead to external infection of the skin, eyes, and mouth, central nervous system (CNS) infection, liver and lung infections. The mortality associated with the Varicella Zoster Virus infection is apprximately 30% and it leads to skin lesions in dermatomal distribution, neurological defects, eye diseases and skeletal abnormalities. Congenital syphilis, HSV and varicellazoster viral infections at prenatal and perinatal stage in women and neonates may cause varying degree of concomitant dermatological manifestations such as non-itchy skin rashes, cold sore, genital sores and vesicular rashes. This review is designed to provide up to date information about the recent development in respect to the mortality associated with TORCH infections and it was believed that the investigation to minimize health-related risk in a particular population, financial burden on health care sectors of the country.

Keywords: Torch infections, pregnancy, seroprevalence.