PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF ASHWAGANDHADI VATI - A FORMULATION FOR ASTHI KSHAYA AND ITS MANAGEMENT
Manisha Lakhi*, Alankruta Dave, Harish C. R. and V. J. Shukla
ABSTRACT
Osteoporosis literally means porous bone. The medical community defines osteoporosis as a skeletal disorder in which bone strength is reduced as a result of loss of bone mass and through the deterioration of the bone architecture. The consequence of these changes is an increased fracture risk. No work has been carried out previously on this Anubhuta formulation. Hence an attempt has been made to study Ashwagandhadi vati by pharmacognostical, physico-chemical parameters and to develop HPTLC (High-Performance Thin Layer chromatography study) fingerprints of the compound formulation of Ashwagandhadi vati. Pharmacognostical work shows that presence of Lignified fibres through medullary rays of Ashwagandha, Border pitted vessel of Ashwagandha, Brown contant of Mandukaparni, Crystaline matirials of Shilajitu, Physico-chemical parameters shows that Ash value percentage4.8 % w/w, Loss on drying percentage2.61 % w/w and Water soluable extract percentage 0.246 % w/w. On performing HPTLC, the chromatogram of Ashwagandhadi vati showed 9 (nine) spotss at short waveUV 254nm; while at long wave UV 366 nm, the chromatogram showed 5 (Five) spots.
Keywords: Ashwagandhadi vati, HPTLC, Pharmacognosy, Physicochemical analysis.
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