European Journal of Biomedical and Pharmaceutical Sciences

GIANT ANTERIOR ABDOMINAL WALL LEIOMYOSARCOMA: CASE REPORT AND REVIEW OF LITERATURE

Dr. Ashish Kumar*

ABSTRACT

Soft tissue sarcomas are one of the rare condition in medical world with occurrence of approximately 1% of adult solid malignant cancer.[1] Almost 50 different histological subtype of sarcoma occur which may arise either from stem cell like population (primitive neuroectodermal tumors) or from morphological recognizable connective tissue.[2] Leiomyosarcoma (LMS) arises from smooth muscles which make up involuntary muscle present in wall of blood vessel, internal organs and skin, are rare aggressive mesenchymal neoplasms accounting 3-7% of soft tissue sarcomas.[3] LMS are divided according to their site into deep soft tissue sites as the retro peritoneum and in peripheral soft tissue sites also known as superficial LMSs. Superficial LMSs are further divided on the basis of their histogenesis and different clinical and prognostic factor into cutaneous and subcutaneous LMSs.[4] Subcutaneous LMSs account for 1-2% of all soft tissue sarcomas[5] and arises from small to medium sized blood vessels present in subcutaneous tissue.[6] Superficial LMSs can occur anywhere in body but lower extremities are most frequent site.[7] The thigh considered to be favorite site[8] and only 10-15% in trunk.[9] and leiomyosarcoma of anterior abdominal wall is very rare.[7] Here we report a case of giant subcutaneous Leiomyosarcoma arising from the anterior abdominal wall.

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