Abstract
EFFICACY OF ASCORBIC ACID AS PROTECTIVE SUBSTANCE ON SODIUM FLUORIDE INDUCED REPRODUCTIVE IMPAIRMENT

Shyamal Kanti Das, Soumendra Nath Karmakar* and Debarati SinghaRoy

ABSTRACT

This study deals with the evaluation of ascorbic acid (Vit-C) as protective agent against Sodium fluoride (NaF) toxicity on male reproductive system. Present Observation clearly reveals the toxic effect of NaF on male reproductive system as body weight, testicular weight, epididymal weight, sperm count, sperm motility, SGPT, SGOT and serum testosterone have been hampered in significant manner. Besides this, improvement or recovery has taken place significantly on these parameters after co-administration or supplement of Vit-c along with NaF. This proves the protective efficacy of Vit-c.

Keywords: Sodium fluoride, ascorbic acid, sperm count, sperm motility, testosterone.


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