PINEAPPLE JUICE ADMINISTRATION POTENTIATE CHANGES IN BODY MASS INDEX, BLOOD GLUCOSE AND SOME HEMATOLOGICAL PARAMETERS IN FEMALE WISTAR RATS
Oyesola A. Olusoji*, Ehichioya E. David, Oyesola O. Tolulope and Kukoyi I. Boone
ABSTRACT
Pineapple juice was reported to have nutritional and clinical role in maintaining a relatively constant and healthy body function during condition of reduced immunity and increase prevalence of infection. This study was conducted to determine nutritional effectiveness of pineapple juice on plasma glucose maintenance, body mass index and some hematological parameters in wistar rats. Eighteen wistar rats, divided into three groups were used: A (control), B and C. Rats in A were administered orally with 0.5 ml volume of water, while rats in B and C were administered orally with 0.5 ml and 1.0 ml volume of pineapple juice respectively for 30 days. Blood samples were collected via cardiac puncture using pentobarbitone as anesthesia. Hematological analysis was carried out using Beckman-coulter hematological analyzer and CD4+ Dynal bead technique. Glucose concentration was determined after enzymatic oxidation and BMI calculated by function of rats’ weights and heights. Statistically analyzed results had significance set at p < 0.05. Rats’ body weight reduced in B significantly and C not significantly when compared with A. Blood glucose levels in both treatment groups as well as CD4+ T cells increased significantly; percentage (note the semi colon) lymphocyte count, percentage neutrophil count of blood in the experimental group B and C increased but not significantly when compared with group A. Consumption of pineapple juice can potentiate increase blood glucose, CD4 count, body mass index, percentage neutrophil count, percentage lymphocyte count, platelet count and body mass index due to the available nutrient present in the juice, mechanism of action need further clarification.
Keywords: Cluster of differentiation 4 count, Hematocrit, Ananas comosus, BMI, Blood glucose.
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