Abstract
ASSESSMENT OF ANTI-ATHEROTHROMBOSIS EFFECT AND PHYTOCHEMICAL SCREENINGS OF ETHANOLIC EXTRACTS OF ALBIZIA CHINENSIS (OSBECK) MERR. BARK

Tasnuva Rubbiat, Md. Hasibul Quader Chowdhury, Md. Areeful Haque*, Mohammed Abu Sayeed and Surajit Barua

ABSTRACT

Atherothrombotic diseases such as cerebral or myocardial infarction are serious consequences of the thrombus formed in blood vessels. Drugs like thrombolytic agents are used to dissolve the formed clots in the blood vessels. But these drugs have certain limitations which may cause serious and sometimes fatal consequences. Herbal preparations have been used as medication since ancient periods for the treatment of diseases of several kinds. The aim of this study was to investigate whether the crude ethanolic extracts of bark of Albizia chinensis (Osbeck) Merr. possess thrombolytic activity or not and at the same time the extract was screened phytochemically to find out the chemically active components by applying standard metdods. In the antiatherothrombosis test, the crude extract exhibited 14.96% clot lysis as compared to the standard, streptokinase (81.08%). Preliminary phytochemical screenings with the crude extract revealed the presence of alkaloids, flavonoids, saponins, reducing sugars, tannins and gums.

Keywords: anti-atherothrombosis, phytochemical screenings, Albizia chinensis barks, ethanolic extract.


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