COMPARISON OF ETHYLENE DICYSTINATE(EC) AND DIETHYLENE TRIAMINE PENTA ACETIC ACID (DTPA) DIURETIC RENOGRAPHY IN EVALUATION OF HYDRONEPHROSIS
*Dr. Venkatesh K. L.
ABSTRACT
Aim: To Compare use of EC and DTPA for diuretic renography in evaluation of hydronephrosis. Methods: All patients with hydronephrosis on ultrasound during the period October 2009 to May 2012 were included in the study. They underwent DTPA diuretic renogram with F-0 protocol. Repeat renogram with EC was done after 48 hours. Parameters studied were isotope uptake, differential function, time activity curves with region of interest (ROI) over the kidney, T1/2, status of drainage in delayed images. Results: 32 children were studied during this period. They were aged 1 month to 11 years with a median age of 8 months). In 14 patients DTPA showed obstructive parameter/s while EC scan showed non obstructive parameter/s excluding obstructive hydronephrosis. In addition EC scan was more accurate in determining differential function in 6 patients in whom DTPA overestimated the function. EC scan also picked up other anomalies like duplex system, ectopic kidney, horseshoe kidney which were not noticed in DTPA. Conclusion: This study demonstrates that EC is more specific in diagnosing obstruction than DTPA, better at calculating split function and in addition detects certain associated anomalies.
Keywords: hydronephrosis, EC, DTPA, diuretic renography.
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