Abstract
HYPOGLYCAEMIC ACTIVITY OF THE LEAVES OF MIMOSA RUBICAULIS (LAM)

Ram Mohan Manda*, Ganapaty Seru

ABSTRACT

Natural products and plant based products have played a vital role in prevention and mitigation of human diseases for centuries, diabetes mellitus is a metabolic disorder is characterized by hyperglycemia, polyuria, polydipsia and polyhagia which are deficient insulin production or ineffectiveness in insulin actions. The present study was aimed to evaluate the anti-diabetic screening of the hydroalcoholic extract of M.rubicaulis leaves was studied on both alloxan induced diabetic rats and normoglycaemic rats, The extract was found to produce marked reduction in blood glucose concentration between 2-4h of administration in both alloxan induced hyperglycaemic and normal glycaemic rats when compared with the reference Glibenclamide. The results indicate that the hydroalcoholic extract of Mimosa rubicaulis is endowed with effective hypoglycaemc effects.

Keywords: Mimosa rubicaulis, Glibenclamide, Alloxan, Hydroalcoholic extract.


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