Abstract
EFFECTS OF METHANOL EXTRACT OF ACIOA BARTERI ON HEPATOCELLULAR DAMAGE AND LIPID PROFILE OF ALBINO RAT

Aloh,G.S., *Obeagu,Emmanuel Ifeanyi, Odo Christian Emeka,  Okpara,kingsley Ezechukwu, Ugwu Getrude Uzoma and Ononogbu, Chimmuanya .E.

ABSTRACT

Methanol extract of Acioa barteri was evaluated for hepatoprotection and lipid profile activities in rats. The plant Extract at (250 and 500mg/kg) showed a significant (P<0.05) hepatoprotective activity against chloroform and hexane induced hepatotoxicity as judged from the serum marker Enzymes and antioxidant levels in liver tissues. Chloroform and hexane induced a significant rise in Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Lipid Peroxidase (LPO), Triglyceride and total cholesterol with a reduction of total protein, Superoxide Dismutase (SOD), Catalase, Glutathione Peroxidase, VIT C and VIT E. Treatment of rats with different doses of plant extract (250 and 500mg/kg) significantly altered serum marker Enzymes (AST and ALT), antioxidant (MDA, GSH, CAT and VIT C) and Lipid profile (TAG) levels to near normal against the chloroform and Hexane induced treated rat, when compared with the controls.

Keywords: Methanol extract, Acioa barteri, hepatoprotection.


[Full Text Article]   [Download Certificate]

Indexing

Indexing

Best Article Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: JULY ISSUE PUBLISHED

    JULY 2026 Issue has been successfully launched on 1 JULY 2026.

  • EJBPS: New Impact Factor 2026

    EJBPS Impact Factor has been Increased from  7.482 to 8.181 for Year 2026.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     
Google Scholar Index Copernicus Indian Science Publications Urlich's Periodicals Directory, Proquest, UK (In Process) Research Bible, Fuchu, Tokyo. JAPAN UDLedge Science Citation Index International Society for Research activity (ISRA) Scientific Indexing Services (SIS) InfoBase Index (In Process) SJIF Impact Factor Scholar Article Impact Factor, SAIF Universal Impact Factor CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Global Impact Factor (GIF) (0.377) IP Indexing (IP Value 3.77) Web of Science Group (Under Process) Directory of Research Journals Indexing Scope Database Academia Academia Doi-Digital Online Identifier Doi-Digital Online Identifier ISSN National Centre Zenodo Indexing International CODEN Service, USA

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT